Patent Number: 10,030,042

Title: Synthesis of bicyclic nucleosides

Abstract: The present disclosure provides methods for synthesizing modified nucleosides, nucleotides, and oligonucleotides comprising at least one 2'-C-Bridged Bicyclic Nucleotide, and to intermediates used in the process.

Inventors: Vagle; Kurt (Boulder, CO)

Assignee: MIRAGEN THERAPEUTICS, INC.

International Classification: C07H 19/00 (20060101); C07H 19/10 (20060101); C07H 19/06 (20060101); C12P 19/38 (20060101); C12P 19/30 (20060101); C07H 19/16 (20060101); C07H 19/073 (20060101); C07H 19/173 (20060101)

Expiration Date: 2022-07-24 0:00:00