Patent Number: 6,165,441

Title: Method of diagnosis and photodynamic therapy of tumours

Abstract: A method of therapeutical treatment of tumors, by photodynamic therapy comprising administering to a subject in need of said treatment an effective amount of a tumor-localizing photosensitizer consisting of a metal phthalocyanine, together with a minor amount of a tracer consisting of said metal phthalocyanine labelled with a radioactive isotope and non-invasively monitoring the concentration of said tracer in the target tumoral tissue and in the peritumoral tissue, thereby to identify the appropriate post-administration interval for performing the photodynamic therapy.

Inventors: Franceschini; Rodolfo (Saluggia, IT), Iori; Giulio (Padua, IT), Polo; Laura (Mestre, IT), Bocchiotti; Giovanni (Turin, IT)

Assignee: Nycomed Amersham Sorin SRL

International Classification: A61K 41/00 (20060101); A61K 51/12 (20060101); A61K 51/02 (20060101); A61K 51/04 (20060101); A61K 051/04 (); A61K 051/12 ()

Expiration Date: 12/26/2017