Patent Number: 6,165,467

Title: Stabilized human monoclonal antibody preparation

Abstract: A stabilized human monoclonal antibody preparation containing 1 to 20 mg of D-mannitol per 1 mg of a human monoclonal antibody. This preparation is excellent in stability in a solution state, a freeze drying state and a freezing state, particularly stability against aggregation and precipitation of the human monoclonal antibody at the time of redissolution after freeze drying.

Inventors: Hagiwara; Hideaki (Takarazuka, JP), Yuasa; Hideo (Kasai, JP), Yamamoto; Yasunori (Kasai, JP)

Assignee: Yoshihide Hagiwara

International Classification: A61K 39/395 (20060101); C07K 016/30 (); A61K 039/395 ()

Expiration Date: 12/26/2017