Patent Number: 6,165,484

Title: EDTA and other chelators with or without antifungal antimicrobial agents for the prevention and treatment of fungal infections

Abstract: A pharmaceutical composition comprising at least one antifungal agent and at least one chelator, and a method for administering the pharmaceutical composition to a patient having a fungal infection. Another aspect provides a pharmaceutical composition comprising at least one chelator, at least one antifungal agent and at least one monoclonal antibody, wherein the monoclonal antibody is operatively attached to the chelator, and a method of administering this composition to a patient having a fungal infection.

Inventors: Raad; Issam (Houston, TX), Sheretz; Robert (Winston-Salem, NC), Hachem; Ray (Houston, TX)

Assignee: Wake Forest University

International Classification: A61K 45/00 (20060101); A61K 45/06 (20060101); A61K 47/16 (20060101); A61K 47/18 (20060101); A01N 025/00 (); A61K 031/70 ()

Expiration Date: 12/26/2017