Patent Number: 6,165,486

Title: Biocompatible compositions and methods of using same

Abstract: Blends of biodegradable polymers, preferably poly(caprolactone) and poly(D,L-lactic-co-glycolic) acid are discussed as well as their applications in the medical field, particularly with regard to bone tissue engineering. Preferably, hydroxyapatite ("HA") granules are incorporated into the blends and the resulting blends have desirable mechanical, physical, and biological characteristics. Even more preferably the compositions of the present invention are utilized to form osteoconductive composites that supported bone cell growth on the surface as well as throughout the scaffold.

Inventors: Marra; Kacey G. (Pittsburg, PA), Weiss; Lee E. (Pittsburg, PA), Calvert; Jay Wynn (Pittsburg, PA), Kumta; Prashant N. (Pittsburg, PA)

Assignee: Carnegie Mellon University

International Classification: A61L 27/00 (20060101); A61L 27/46 (20060101); A61F 002/00 (); A61F 013/00 ()

Expiration Date: 12/26/2017