Patent Number: 6,165,489

Title: Crosslinked collagen compositions for in situ administration

Abstract: The present invention discloses a novel, injectable crosslinked collagen composition which is able to continue crosslinking after injection to a soft or hard tissue site in order to anchor the collagen implant to the host tissue. The composition comprises particulate crosslinked collagen, noncrosslinked collagen (which may be fibrillar or nonfibrillar collagen), and a chemical crosslinking agent, such as synthetic hydrophilic polymer. Methods of augmenting soft or hard tissue using these injectable collagen compositions are also disclosed.

Inventors: Berg; Richard A. (Los Altos, CA), Rosenblatt; Joel S. (Palo Alto, CA), Rhee; Woonza M. (Palo Alto, CA)

Assignee: Cohesion Technologies, Inc.

International Classification: A61L 27/00 (20060101); A61L 27/18 (20060101); A61L 27/24 (20060101); A61L 26/00 (20060101); A61L 31/04 (20060101); C07K 14/435 (20060101); C07K 14/78 (20060101); C08L 89/00 (20060101); C08L 89/06 (20060101); A61F 2/00 (20060101); A61F 002/02 ()

Expiration Date: 12/26/2017