Patent Number: 6,165,492

Title: Intrauterine chemical necrosing method, composition, and apparatus

Abstract: A method and composition for effecting chemical necrosis of a tissue lining of a mammalian body cavity, particularly a uterine endometrium, by delivering a caustic tissue necrosing composition, e.g., a silver nitrate and dextran paste, to the tissue to be necrosed and allowing the paste to remain in contact with the target tissue for a period of time sufficient to chemically necrose substantially the entirety of the tissue lining, and then contacting the caustic composition with a deactivating agent, e.g., an aqueous sodium chloride solution, thereby rendering the caustic composition non-caustic, and then rinsing the cavity. Compositions and methods for delivering medicaments are also disclosed.

Inventors: Neuwirth; Robert S. (Englewood, NJ)


International Classification: A61K 9/00 (20060101); A61K 47/36 (20060101); A61F 006/06 (); A61M 013/00 ()

Expiration Date: 12/26/2013