Patent Number: 6,165,502

Title: Protein-lipid vesicles and autogenous vaccine comprising the same

Abstract: A protein-lipid vesicle that can be used to make an autogenous vaccine comprises patient-specific antigen, adjuvant or immunomodulator, and lipid carrier. In addition, a negatively charged lipid component is desirably included. The autogenous vaccine is useful to treat individuals with chronic diseases, including chronic infectious diseases and neoplasias. The chronic infectious diseases that can be treated include disease caused by infection with human immunodeficiency viruses.

Inventors: Oleske; James M. (Morris Plains, NJ), Denny; Thomas N. (Cranford, NJ), Scolpino; Anthony J. (Ramsey, NJ), Feketeova; Eleonora (Harrison, NJ), Gould-Fogerite; Susan (Annandale, NJ), Mannino; Raphael J. (Annandale, NJ)

Assignee: Albany Medical College

International Classification: A61K 9/00 (20060101); A61K 9/127 (20060101); A61K 009/127 ()

Expiration Date: 12/26/2017