Patent Number: 6,165,513

Title: Film-coated tablet for improved upper gastrointestinal tract safety

Abstract: A novel oral dosage to be delivered to the stomach comprising a safe and effective amount of an active ingredient selected from the group consisting of emepronium bromidebromide, doxycycline, and other tetracyclines/antibiotics, iron preparations, quinidine, nonsteroidal anti-inflammatory drugs, alprenolol, ascorbic acid, captopril, theophylline, zidovoudine (AZT), bisphosphonates and mixtures thereof and pharmaceutically-acceptable excipients, wherein said oral dosage form is a generally oval form and film coated to facilitate rapid esophageal transit and avoid irritation in the mouth, buccal cavity, pharynx, and esophagus.

Inventors: Dansereau; Richard John (Mason, OH), Bekker; Petrus Jakobus (Cincinnati, OH)

Assignee: The Procter & Gamble Co.

International Classification: A61K 31/65 (20060101); A61K 31/675 (20060101); A61K 9/28 (20060101); A61K 31/138 (20060101); A61K 31/401 (20060101); A61K 31/375 (20060101); A61K 31/519 (20060101); A61K 31/49 (20060101); A61K 31/522 (20060101); A61K 009/16 (); A61K 009/50 ()

Expiration Date: 12/26/2017