Patent Number: 6,165,716

Title: Screening for disorders of serotonergic dysfunction

Abstract: Three novel alleles of the serotonin transporter gene are disclosed and shown to be effective markers for screening and diagnosis of migraine and psychiatric disorders. The sequences of the alleles are given. Methods for in vitro screening of individuals using DNA taken from blood samples are taught.

Inventors: Battersby; Sharon (Edinburgh, GB), Fink; George (Edinburgh, GB), Goodwin; Guy Manning (Edinburgh, GB), Harmar; Anthony John (Edinburgh, GB), Ogilvie; Alan David (Edinburgh, GB), Smith; Christopher Albert Dale (Edinburgh, GB)

Assignee: Medical Research Council

International Classification: C07K 14/435 (20060101); C07K 14/47 (20060101); C12Q 001/08 (); C07H 021/02 (); C07H 021/04 ()

Expiration Date: 12/26/2017