Patent Number: 6,165,728

Title: Antisense modulation of NCK-2 expression

Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of nck-2. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding nck-2. Methods of using these compounds for modulation of nck-2 expression and for treatment of diseases associated with expression of nck-2 are provided.

Inventors: Ward; Donna T. (San Diego, CA), Cowsert; Lex M. (Carlsbad, CA)

Assignee: Isis Pharmaceuticals Inc.

International Classification: C12N 15/11 (20060101); A61K 38/00 (20060101); C07H 021/04 (); C12Q 001/68 (); C12N 015/85 ()

Expiration Date: 12/26/2013