Patent Number: 6,165,735

Title: Parasitic helminth asparaginase proteins, nucleic acid molecules, and uses thereof

Abstract: The present invention relates to: parasitic helminth asparaginase proteins; parasitic helminth asparaginase nucleic acid molecules, including those that encode such asparaginase proteins; antibodies raised against such asparaginase proteins; and compounds that inhibit parasitic helminth asparaginase activity. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to protect animals from diseases caused by parasitic helminths.

Inventors: Chandrashekar; Ramaswamy (Fort Collins, CO), Tsuji; Naotoshi (Fort Collins, CO)

Assignee: Heska Corporation

International Classification: C12N 9/82 (20060101); C12N 9/78 (20060101); A61K 38/00 (20060101); A61K 39/00 (20060101); G01N 033/53 (); G01N 033/569 (); C07K 016/00 (); C12P 021/08 (); A61K 039/395 ()

Expiration Date: 12/26/2017