Patent Number: 6,166,066

Title: Cannabinoids selective for the CB2 receptor

Abstract: Disclosed are novel cannabinoids which are selective for the CB2 receptor. The novel cannabinoids comprise a substituted or unsubstituted tricyclic cannabinoid core and a substituted or unsubstituted C5-C8 carbocyclic ring, five to eight-membered heterocyclic ring or a seven to ten membered bicyclic ring system fused to the monhydroxylated phenyl ring of the cannabinoid core. Also disclosed are methods of suppressing the immune system in a subject by administering to the subject a (e.g. immunosuppressive amount) effective amount of a novel cannabinoid described above.

Inventors: Makriyannis; Alexandros (Willimantic, CT), Khanolkar; Atmaram (Storrs, CT), Lu; Dai (Storrs, CT)

Assignee: The University of Connecticut

International Classification: C07D 311/00 (20060101); C07D 311/78 (20060101); A61K 031/35 ()

Expiration Date: 12/26/2013