Patent Number:
6,166,088
Title:
Benzamidine derivatives substituted by amino acid and hydroxy acid derivatives and their use as anti-coagulants
Abstract:
This invention is directed to benzamidine derivatives substituted by amino acid and hydroxy acid derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.
Inventors:
Kochanny; Monica (San Rafael, CA), Mohan; Raju (Moraga, CA), Morrissey; Michael M. (Danville, CA), Ng; Howard P. (El Sobrante, CA), Yun; Weiya (Richmond, CA)
Assignee:
Berlex Laboratories, Inc.
International Classification:
C07D 401/12 (20060101); C07D 401/00 (20060101); A61K 031/155 (); C07C 257/18 ()
Expiration Date:
12/26/2017