Patent Number: 6,166,177

Title: Compounds and methods for the treatment and diagnosis of chlamydial infection

Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydial antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.

Inventors: Probst; Peter (Seattle, WA), Bhatia; Ajay (Seattle, WA), Skeiky; Yasir A. W. (Seattle, WA)

Assignee: Corixa Corporation

International Classification: C07K 14/295 (20060101); C07K 14/195 (20060101); A61K 39/00 (20060101); A61K 038/00 (); C07K 014/00 (); C07K 016/00 (); C07K 017/00 (); C07H 021/04 ()

Expiration Date: 12/26/2013