Patent Number: 6,166,180

Title: Chromosome 21 gene marker, compositions and methods using same

Abstract: The present invention provides isolated nucleic acids encoding human EHOC-1 protein and isolated receptor proteins encoded thereby. Further provided are vectors containing invention nucleic acids, probes that hybridize thereto, host cells transformed therewith, antisense oligonucleotides thereto and compositions containing, antibodies that specifically bind to invention polypeptides and compositions containing, as well as transgenic non-human mammals that express the invention protein.

Inventors: Korenberg; Julie R. (Los Angeles, CA), Yamakawa; Kazuhiro (Los Angeles, CA)

Assignee: Cedar-Sinai Medical Center

International Classification: C07K 14/435 (20060101); C07K 14/47 (20060101); A61K 48/00 (20060101); C07K 014/47 ()

Expiration Date: 12/26/2017