Patent Number: 6,166,181

Title: Human adenosine receptors

Abstract: The invention concerns recombinant human adenosine receptors A1, A2a, A2b and A3 which have been prepared by cDNA cloning and polymerase chain reaction techniques. The invention also concerns expression systems for these receptors and an assay using the expression systems. The recombinant adenosine receptors comprising the invention can be utililized in an assay to identify and evaluate entities that bind to or enhance binding to adenosine receptors.

Inventors: Jacobson; Marlene A. (Elkins Park, PA), Luneau; Christopher J. (Lansdale, PA), Johnson; Robert G. (Rosemont, PA), Salvatore; Christopher A. (North Wales, PA)

Assignee: Merck & Co., Inc.

International Classification: C07K 14/435 (20060101); C07K 14/705 (20060101); C07K 014/705 (); C12N 015/12 ()

Expiration Date: 12/26/2013