Patent Number: 6,166,186

Title: Monoclonal antibody which binds to a human-Th2-specific protein and hybridoma

Abstract: The present specification provides a means for specifying the condition and type of immune-related diseases on the basis of knowledge about the polarization of the distribution of helper T-cell subsets Th1 and Th2. More specifically, the gene (B19), specific only to the human Th2, is prepared by a subtraction method. A human-Th2-specific protein which the gene encodes is produced by recombinant methods, and a monoclonal antibody against the Th2-specific protein and a hybridoma which produces the monoclonal antibody is provided.

Inventors: Ogawa; Kazuyuki (Saitama, JP), Tanaka; Kazuya (Saitama, JP), Nagata; Kinya (Saitama, JP), Takano; Syoichi (Saitama, JP)

Assignee: BML, Inc.

International Classification: C07K 14/435 (20060101); C07K 14/47 (20060101); C07K 14/705 (20060101); C07K 16/28 (20060101); C07K 16/18 (20060101); A61K 38/00 (20060101); C12N 005/12 (); C07K 016/44 ()

Expiration Date: 12/26/2017