Patent Number: 6,166,200

Title: Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes

Abstract: Cascade polymer complexes that containa) complexing ligands of general formula Iin whichA stands for a nitrogen-containing cascade nucleus of base multiplicity a,X and Y, independently of one another, stand for a direct bond or a cascade reproduction unit of reproduction multiplicity x or y,Z and W, independently of one another, stand for a cascade reproduction unit of reproduction multiplicity z or w,K stands for the radical of a complexing agent,a stands for numbers 2 to 12,x, y, z and w, independently of one another, stand for numbers 1 to 4,provides that at least two reproduction units are different and that for the product of the multiplicities,holds true,b) at least 16 ions of an element of atomic numbers 20 to 29, 39, 42, 44 or 57-83,c) optionally cations of inorganic and/or organic bases, amino acids or amino acid amides as well asd) optionally acylated terminal amino groups are valuable compounds for diagnosis and therapy.

Inventors: Schmitt-Willich; Heribert (Berlin, DE), Platzek; Johannes (Berlin, DE), Raduchel; Bernd (Berlin, DE), Muhler; Andreas (Neuenhagen, DE), Frenzel; Thomas (Berlin, DE)

Assignee: Schering Aktiengesellschaft

International Classification: A61K 49/06 (20060101); A61K 49/08 (20060101); C07C 229/76 (20060101); C07C 229/00 (20060101); C07C 237/42 (20060101); C07C 237/00 (20060101); C07D 487/00 (20060101); C07D 487/08 (20060101); C07D 251/54 (20060101); C07D 257/00 (20060101); C07D 251/00 (20060101); C07D 257/02 (20060101); C07K 14/00 (20060101); C07D 255/02 (); C07D 225/00 (); A61B 005/055 (); A61K 051/00 (); C07F 005/00 ()

Expiration Date: 12/26/2013