Patent Number: 6,166,224

Title: Method for racemization of optically active azetidine-2-carboxylate

Abstract: A method for racemization of an optically active N-substituted azetidine-2-carboxylic acid ester of the formula (1): ##STR1## wherein * represents an asymmetric carbon atom, R.sup.1 represents an aryl, R.sup.2 represents a saturated hydrocarbon group which may be substituted, which is characterized by heating the ester at 100.degree. C. or higher, or subjecting the ester to contact with a basic compound selected from an alkali metal hydride, an alkali metal alcoholate of tertiary alcohol and an organic amine.

Inventors: Hirata; Norihiko (Suita, JP), Kurimoto; Isao (Suita, JP)

Assignee: Sumitomo Chemical Company, Limited

International Classification: C07D 205/00 (20060101); C07D 205/04 (20060101); C07D 205/04 ()

Expiration Date: 12/26/2017