Patent Number: 6,167,880

Title: Inhaled insulin dosage control delivery enhanced by controlling total inhaled volume

Abstract: Dosages of inhaled insulin are controlled within a narrow range by controlling the total volume of air inhaled by a patient. By repeatedly delivering aerosolized insulin with the same total inhaled volume of air, the amount of insulin delivered to the patient each time is consistent. A device for delivering insulin by inhalation is disclosed which device comprises a means for measuring inhaled volume and for halting inhalation at a pre-determined point. The device also comprises an adjustable means for applying various amounts of force to a container of formulation to expel different amounts of drug from the container based on the force applied.

Inventors: Gonda; Igor (San Francisco, CA), Rubsamen; Reid M. (Oakland, CA), Farr; Stephen J. (Orinda, CA)

Assignee: Aradigm Corporation

International Classification: A61K 38/28 (20060101); A61M 15/00 (20060101); A61J 7/04 (20060101); A61J 7/00 (20060101); A61M 16/10 (20060101); A61M 16/14 (20060101); A61M 16/00 (20060101); A61M 011/00 ()

Expiration Date: 01/02/2018