Patent Number: 6,167,888

Title: Method for inducing partial recovery of lost voluntary motor function after spinal cord injury in a mammal

Abstract: The invention provides means for inducing partial recovery of motor function lost in a mammal as a consequence of an injury to its spinal cord which includes a lesion of the cerebrospinal projections (CST) of the cord. Axonal growth is initiated in the CST, and functional recovery obtained, by delivering neurotrophin-3 to the site of CST injury by expression from a recombinant expression vector.

Inventors: Tuszynski; Mark H. (La Jolla, CA), Grill; Rav (San Diego, CA), Gage; Fred H. (La Jolla, CA)

Assignee: The Regents of the University of California

International Classification: A61K 38/18 (20060101); A61B 019/00 ()

Expiration Date: 01/02/2018