Patent Number: 6,168,785

Title: Biological applications of new peptides of IL-2 and derivatives and use as therapeutic agents

Abstract: The invention relates to the use as therapeutic agents of IL-2 peptides and derivatives having biological activity and anti-IL-2 antibodies which mimic or modulate the biological activities of IL-2. The invention also relates to DNA sequences encoding the IL-2 peptides, and to methods of using the IL-2 peptides and derivatives and anti-IL-2 antibodies to modulate or mimic or antagonize the biological activities of IL-2 in vivo and to assay for the presence and activity of the IL-2 receptor.

Inventors: Theze; Jacques (Paris, FR), Eckenberg; Ralph (Germain en Laye, FR), Moreau; Jean-Louis (Paris, FR), Mazie; Jean-Claude (Asnieres-sur-Seine, FR)

Assignee: Institut Pasteur

International Classification: C07K 14/435 (20060101); C07K 14/55 (20060101); C07K 16/24 (20060101); C07K 16/18 (20060101); G01N 33/68 (20060101); A61K 38/00 (20060101); A61K 038/20 ()

Expiration Date: 01/02/2018