Patent Number: 6,168,786

Title: Chimeric immunogens

Abstract: Multimeric hybrid genes encoding the corresponding chimeric protein comprise a gene sequence coding for an antigenic region of a protein from a first pathogen linked to a gene sequence coding for an antigenic region of a protein from a second pathogen. The pathogens particularly are parainfluenza virus (PIV) and respiratory syncytial virus (RSV). A single recombinant immunogen is capable of protecting infants and similar susceptible individuals against diseases caused by both PIV and RSV.

Inventors: Klein; Michel H. (Willowdale, CA), Du; Run-Pan (Thornhill, CA), Ewasyshyn; Mary E. (Willowdale, CA)

Assignee: Connaught Laboratories Limited

International Classification: C07K 14/135 (20060101); C07K 14/005 (20060101); C07K 14/115 (20060101); G01N 33/569 (20060101); A61K 39/00 (20060101); A01N 063/00 (); A61K 039/395 (); A61K 039/00 (); A61K 039/12 ()

Expiration Date: 01/02/2018