Patent Number: 6,168,798

Title: Non-irritating composition for treating acne and other skin conditions

Abstract: The invention provides methods and compositions which are mild and nonirritating for reducing and eliminating skin disorders, particularly blemishes and redness associated with acne. The hydroalcoholic compositions of the invention contain a keratolytic compound, preferably a .beta.-hydroxy carboxylic acid, more preferably salicylic acid or pharmaceutically acceptable salt thereof; and a glycerophosphate ester or salt, formulated with pharmaceutically acceptable carriers. Preferred glycerophosphate salts for use in the methods and compositions of the invention are sodium glycerophosphate and calcium glycerophosphate. Additional anti-irritancy agents are not required in the compositions of the present invention, as the glycerophosphate salt component uniquely endows the compositions with nonirritant properties. Other components which may be formulated into the compositions of the invention include fragrances, colorants, emollients, humectants and antimicrobial agents.

Inventors: O'Halloran; David P. (Milltown, NJ), Rudtke; Deborah (Hillsdale, NJ), Mayes-Smith; Joyce (North Brunswick, NJ)

Assignee: Bristol-Myers Squibb Company

International Classification: A61K 8/55 (20060101); A61K 8/30 (20060101); A61K 8/368 (20060101); A61Q 17/00 (20060101); A61Q 19/00 (20060101); A61K 007/48 ()

Expiration Date: 01/02/2018