Patent Number: 6,168,929

Title: Method of identifying agents that disrupt the interaction of SV40 T antigen with Dnak homologues

Abstract: The present invention provides a method of identifying agents that interfere with the interaction of the J-domain of the SV40 large T antigen with a Dnak protein. In a preferred embodiment, the Dnak protein is mammalian hsc70 or yeast Ssa1p.

Inventors: Pipas; James M. (Pittsburgh, PA), Brodsky; Jeffrey L. (Pittsburgh, PA)

Assignee: University of Pittsburgh

International Classification: C07K 14/005 (20060101); C07K 14/025 (20060101); C12Q 1/42 (20060101); G01N 33/50 (20060101); C12Q 001/44 (); C07K 014/025 ()

Expiration Date: 01/02/2018