Patent Number: 6,168,942

Title: Attenuated forms of bovine viral diarrhea virus

Abstract: The present invention is directed to a method of producing attenuated forms of bovine viral diarrhea (BVD) virus by mutating the N.sup.pro protease gene. The invention includes the attenuated viruses made by this method, antibodies generated using these viruses, and vaccines that can be used for immunizing cattle.

Inventors: Cao; Xuemei (East Lyme, CT), Sheppard; Michael G. (Stonington, CT)

Assignee: Pfizer Inc.

International Classification: A61K 39/12 (20060101); C07K 14/005 (20060101); C07K 14/18 (20060101); C12N 7/04 (20060101); C12N 007/04 ()

Expiration Date: 01/02/2018