Patent Number: 6,169,065

Title: Method for the activity of an enzyme

Abstract: There is provided a process for enhancing the activity of an oxidoreductase, comprising adding to the enzyme, as an enhancer for the activity of said enzyme, a compound having the formula: ##STR1## wherein X represents (--O--) or (--S--) and R.sup.1, R.sup.2 and R.sup.3 may each independently represent hydrogen, hydroxy, halogen, nitroso, formyl, carboxyl, and esters and salts thereof, carbamoyl, sulfo, and esters and salts hereof, sulfamoyl, nitro, amino, phenyl, C.sub.1 -C.sub.20 alkyl, C.sub.1 -C.sub.8 alkoxy, carbonyl-C.sub.1 -C.sub.6 -alkoxy, aryl-C.sub.1 -C.sub.6 -alkyl, whereby: the carbamoyl, sulfamoyl and amino groups may be unsubstituted or substituted once or twice with hydroxy, C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.6 -alkoxy, in which C.sub.1 -C.sub.6 -group may be saturated or unsaturated, branched or unbranched and may be substituted once or twice with halogen, nitroso, hydroxy, formyl, carboxy, and esters and salts thereof, carbamoyl, sulfo, and esters and salts hereof, sulfamoyl; and the phenyl group may be substituted with once or twice with halogen, nitroso, hydroxy, formyl, carboxy, and esters and salts thereof, carbamoyl, sulfo, and esters and salts hereof, sulfamoyl; and the C.sub.1 -C.sub.20 alkyl, C.sub.1 -C.sub.8 alkoxy, carbonyl-C.sub.1 -C.sub.6 -alkoxy, and aryl-C.sub.1 -C.sub.6 -alkyl groups may be saturated or unsaturated, branched or unbranched, and may be substituted with halogen, hydroxy, nitroso, formyl, carboxy, and esters and salts thereof, carbamoyl, sulfo, and esters and salts thereof, sulfamoyl, nitro, amino, phenyl, aminoalkyl, piperidino, piperazinyl, pyrrolidin-2-yl, C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.6 -alkoxy; whereby two or more of the groups R.sup.1 -R.sup.3 may be linked together by any group, and and A and B represent at least one six membered heterocyclic ring which may be optionally substituted with one or more of any of the radicals as defined for R.sup.1 -R.sup.3.

Inventors: Antheunisse; Willem (Vlaardingen, NL), Hage; Ronald (Vlaardingen, NL), Hora; Jiri (Den Haag, NL), Swarthoff; Ton (Vlaardingen, NL), Twisker; Robin Stefan (Vlaardingen, NL)

Assignee: Lever Brothers Company division of Conopco Company

International Classification: C11D 3/28 (20060101); C11D 3/00 (20060101); C11D 3/38 (20060101); C11D 3/386 (20060101); C11D 3/26 (20060101); C11D 3/34 (20060101); C11D 003/386 (); C11D 003/395 ()

Expiration Date: 01/02/2018