Patent Number: 6,169,072

Title: Cyclic adhesion inhibitors

Abstract: The invention relates to novel cyclopeptides of the formula I in which B, D, and E have the meanings defined herein, and their salts. These compounds act as interin inhibitors and can be used, in particular, for the prophylaxis and treatment of disorders of the circulation and in tumor therapy.

Inventors: Jonczyk; Alfred (Darmstadt, DE), Holzemann; Gunter (Seeheim-Jugenheim, DE), Felding-Habermann; Brunhilde (La Jolla, CA), Rippmann; Friedrich (Heidelberg, DE), Diefenbach; Beate (Darmstadt, DE), Kessler; Horst (Schwalbach, DE), Haubner; Roland (Garching, DE), Wermuth; Jochen (Garching, DE)

Assignee: Merck Patent Gesellschaft Mit

International Classification: C07K 14/435 (20060101); C07K 14/75 (20060101); A61K 38/00 (20060101); A61K 038/00 (); A61K 038/12 (); A61K 038/08 (); C07K 007/64 ()

Expiration Date: 01/02/2018