Patent Number: 6,169,111

Title: Conformationally rigid aryl prostaglandins for use in glaucoma therapy

Abstract: Conformationally rigid aryl prostaglandins are useful in the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic pharmaceutical compositions comprising said prostaglandins.

Inventors: Zinke; Paul W. (Fort Worth, TX), Bishop; John E. (Groton, MA), Dean; Thomas R. (Weatherford, TX), Hellberg; Mark R. (Arlington, TX)

Assignee: Alcon Laboratories, Inc.

International Classification: A61K 31/557 (20060101); A61K 31/5575 (20060101); C07C 405/00 (20060101); A61K 031/557 ()

Expiration Date: 01/02/2018