Patent Number: 6,169,173

Title: Cloning and functional expression of cholecystokinin/gastrin receptor-encoding DNA

Abstract: An unconventional approach to purifying CCK receptor protein to sequenceable-grade homogeneity has been discovered. By this approach, CCK receptor protein can be obtained and sequenced routinely from a variety sources, and from the sequence information thus obtained it is possible to prepare oligonucleotides suitable for cloning CCK receptor genes. "CCK receptor" in this context denotes, any from a group of proteins that displays a characteristic CCK binding affinity and that is encoded by a nucleotide sequence which hybridizes a oligonucleotide probe designed in accordance with the criteria elaborated herein.

Inventors: Wank; Stephen A. (Bethesda, MD)

Assignee: The United States of America as represented by the Department of Health and Human Services

International Classification: C07K 14/435 (20060101); C07K 14/705 (20060101); C12N 015/12 ()

Expiration Date: 01/02/2018