Patent Number: 6,169,183

Title: Process for preparing pyridinecarboxylic esters

Abstract: A process for preparing pyridinecarboxylic esters of the general formula: ##STR1## wherein R.sup.1 is hydrogen, a C.sub.1-6 -alkyl group, a C.sub.1-4 -alkoxycarbonyl group, a C.sub.1-4 -alkoxymethyl group or a fluorinated C.sub.1-6 -alkyl group, R.sup.2 is a C.sub.1-4 -alkyl group and X is chlorine or bromine. The pyridinecarboxylic esters are obtained by reacing the corresponding 2,3-dihalopyridines with carbon monoxide and a C.sub.1-4 -alkanol in the presence of a weak base and a complex of palladium with a bis(diphenylphosphine). Pyridinecarboxylic esters are intermediates for preparing herbicides and drugs against fibrotic diseases.

Inventors: Bessard; Yves (Sierre, CH), Stucky; Gerhard (Brig-Glis, CH), Roduit; Jean-Paul (Grone, CH)

Assignee: Lonza, Ltd.

International Classification: C07D 213/00 (20060101); C07D 213/61 (20060101); C07D 213/79 (20060101); C07D 213/80 (20060101); C07D 213/30 ()

Expiration Date: 01/02/2018