Patent Number: 6,169,205

Title: Process for the purification of (RR,SS)-2-(dimethylamino) methyl-1-(3-methoxyphenyl)-cyclohexanol from (RS,SR)-2-(dimethylamino)methyl-1-(3-methoxyphenyl) cyclohexanol

Abstract: A process for the purification of (RR,SS)-2-(dimethylamino)methyl-1-(3-methoxyphenyl)cyclohexanol, which comprises the selective precipitation of (RR,SS)-2-(dimethylamino)methyl-1-(3-methoxyphenyl)cyclohexanol in the presence of (RS,SR)-2-(dimethylamino)methyl-1-(3-methoxyphenyl)cyclohexanol from a solvent consisting of water and a water-miscible organic solvent.

Inventors: Cabri; Walter (Baranzate di Bollate, IT), Magrone; Domenico (Baranzate di Bollate, IT)

Assignee: Dipharma S.p.A.

International Classification: C07C 213/10 (20060101); C07C 213/00 (20060101); C07C 217/00 (20060101); C07C 217/74 (20060101); C07C 211/00 ()

Expiration Date: 01/02/2018