Patent Number: 6,169,919

Title: System and method for quantifying alternation in an electrocardiogram signal

Abstract: A system and method for quantifying alternation in the T-wave and ST segment of an ECG signal receives a digitized ECG signal (i.e., ECG data) for processing. The ECG data are used to calculate an odd median complex for the odd beats in the ECG data and an even median complex for the even beats in the ECG data. The odd median complex and the even median complex are then compared to obtain an estimate of the amplitude of beat-to-beat alternation in the ECG signal. Prior to calculation of the even and odd median complexes, the ECG data are filtered. Filtering of the ECG data involves low pass filtering the ECG data to remove high frequency noise, applying a baseline wander removal filter to the ECG data to remove low frequency artifacts, removing arrhythmic beats from the ECG data, and eliminating noisy beats from the ECG data. The filtered data are more suitable for calculation of an accurate estimate of alternation.

Inventors: Nearing; Bruce D. (North Reading, MA), Verrier; Richard L. (Wellesley, MA)

Assignee: Beth Israel Deaconess Medical Center, Inc.

International Classification: A61B 5/0452 (20060101); G06F 17/00 (20060101); A61B 005/0452 ()

Expiration Date: 01/02/2018