Patent Number: 6,183,772

Title: Doped colorimetric assay liposomes

Abstract: The present invention provides compositions comprising colorimetric assay liposomes. The present invention also provides methods for producing colorimetric liposomes and calorimetric liposome assay systems. In preferred embodiments, these calorimetric liposome systems provide high levels of sensitivity through the use of dopant molecules. As these dopants allow the controlled destabilization of the liposome structure, upon exposure of the doped liposomes to analyte(s) of interest, the indicator color change is facilitated and more easily recognized.

Inventors: Charych; Deborah (Albany, CA), Stevens; Raymond C. (Albany, CA)


International Classification: A61K 9/127 (20060101); G01N 33/58 (20060101); A61K 009/127 (); A61K 049/00 (); G01N 033/53 (); G01N 033/544 ()

Expiration Date: 02/06/2013