Patent Number: 6,183,781

Title: Method for fabricating polymer-based controlled-release devices

Abstract: The present invention includes a method for producing an implantable polymer/drug matrix mass, comprising the steps of (1) forming a polymer solution/drug mixture comprising a polymer dissolved in an organic solvent and a suspended labile drug; (2) removing the solvent from the polymer solution/drug mixture, thereby forming a solid polymer/drug matrix; and (3) mechanically compressing the polymer/drug matrix, thereby forming an implantable polymer/drug matrix mass.

Inventors: Burke; Paul A. (Medford, MA)

Assignee: Alkermes Controlled Therapeutics, Inc.

International Classification: A61K 38/18 (20060101); A61K 9/00 (20060101); A61K 9/16 (20060101); A61K 38/00 (20060101); A61K 009/10 (); A61K 009/14 ()

Expiration Date: 02/06/2018