Patent Number: 6,200,592

Title: Immine response modifier compounds for treatment of TH2 mediated and related diseases

Abstract: Immune response modifier compounds--imidazoquinoline amines, imidazopyridine amines, 6,7-fused cycloalkylimidazopyridine amines, and 1,2-bridged imidazoquinoline amines--are useful for the treatment of TH2 mediated diseases by administering a therapeutically effective amount of such compounds in order to inhibit TH2 immune response, suppress IL-4/IL-5 cytokine induction and eosinophilia, as well as enhance TH1 immune response.

Inventors: Tomai; Mark A. (Oakdale, MN), Hammerbeck; David M. (Houlton, WI), Swingle; Karl F. (Oakdale, MN)

Assignee: 3M Innovative Properties Company

International Classification: A61K 31/437 (20060101); A61K 31/4353 (20060101); A61K 31/4738 (20060101); A61K 31/4748 (20060101); A61K 31/4745 (20060101); A61F 013/02 ()

Expiration Date: 03/13/2018