Patent Number: 6,200,769

Title: Mammalian CDP-diacylglycerol synthase

Abstract: There is disclosed cDNA sequences and polypeptides having the enzyme CDP-diacylglycerol synthase (CDS) activity. CDS is also known as CTP:phosphatidate cytidylyltransferase. There is further disclosed methods for isolation and production of polypeptides involved in phosphatidic acid metabolism and signaling in mammalian cells, in particular, the production of purified forms of CDS.

Inventors: Leung; David W. (Mercer Island, WA), Weeks; Reitha (Seattle, WA)


International Classification: C12N 9/12 (20060101); C12Q 001/48 (); C12N 009/10 ()

Expiration Date: 03/12013