Patent Number: 6,251,136

Title: Method of layering a three-coated stent using pharmacological and polymeric agents

Abstract: A pharmacological agent is applied to a stent in dry, micronized form over a sticky base coating. A membrane forming polymer, selected for its ability to allow the diffusion of the pharmacological agent therethrough, is applied over the entire stent. More specifically, a stent, typically a metal stent, has a layer of a sticky material applied to selected surfaces of the stent. A pharmacological agent is layered on the sticky material and a membrane forming a polymer coating is applied over the pharmacological agent. The membrane is formed from a polymer that permits diffusion of the pharmacological agent over a predetermined time period.

Inventors: Guruwaiya; Judy A. (San Jose, CA), Millare; Deborra Sanders (San Jose, CA), Wu; Steven Z-H (Santa Clara, CA)

Assignee: Advanced Cardiovascular Systems, Inc.

International Classification: A61F 2/06 (20060101); A61L 31/14 (20060101); A61L 31/16 (20060101); A61L 31/10 (20060101); A61L 31/08 (20060101); A61F 002/06 ()

Expiration Date: 06/26/2018