Patent Number: 6,251,368

Title: Pharmaceutical aerosol formulation containing a particulate medicament, a propellant and substantially free of a surfactant

Abstract: A pharmaceutical aerosol formulation which comprises particulate medicament selected from the group consisting of salmeterol, salbutamol, fluticasone propionate, beclomethasone dipropionate and physiologically acceptable salts and solvates thereof and a fluorocarbon or hydrogen-containing chlorofluorocarbon propellant, which formulation is substantially free of surfactant is disclosed. Also disclosed is a method of treating respiratory disorders which comprises administration by inhalation of an effective amount of the, pharmaceutical aerosol formulation which may be contained in a canister.

Inventors: Akehurst; Rachel Ann (Ware, GB), Taylor; Anthony James (Ware, GB), Wyatt; David Andrew (Ware, GB)

Assignee: Glaxo Group Limited

International Classification: A61K 45/00 (20060101); A61K 9/12 (20060101); A61K 31/135 (20060101); A61K 31/137 (20060101); A61K 31/167 (20060101); A61K 31/138 (20060101); A61K 45/06 (20060101); A61K 31/4402 (20060101); A61K 31/352 (20060101); A61K 31/44 (20060101); A61K 31/4738 (20060101); A61K 31/519 (20060101); A61K 31/57 (20060101); A61K 31/4741 (20060101); A61K 31/4535 (20060101); A61K 31/4458 (20060101); A61K 31/573 (20060101); A61K 31/56 (20060101); A61K 31/48 (20060101); A61K 31/4523 (20060101); A61K 31/522 (20060101); A61K 009/12 ()

Expiration Date: 06/26/2018