Patent Number: 6,251,370

Title: Tissue adhesive suitable for spray application

Abstract: An adhesive for tissue capable of uniformly forming a high concentration of fibrin so as to provide a high closing effect is disclosed. The adhesive for tissue comprises a fibrinogen solution and a thrombin solution which solutions are separated from each other. The adhesive is to be mixed and spray coated together with a sterile gas and has a volume ratio of the fibrinogen solution to the thrombin solution of about 2:1 to 10:1. This adhesive is to be sprayed together with a sterile gas for the adhesion or closing of living tissue of a human being or animal.

Inventors: Uchida; Takanori (Kumamoto, JP), Kaetsu; Hiroshi (Nishigoushi-machi, JP), Fukunaga; Nobuto (Tamana, JP), Shinya; Noriko (Kumamoto, JP), Sakamoto; Takahiro (Goushi-machi, JP)

Assignee: Juridical Foundation The Chemosero Therapeutic Research Institute

International Classification: A61L 24/10 (20060101); A61L 24/00 (20060101); A61B 17/00 (20060101); A61L 009/04 ()

Expiration Date: 06/26/2018