Patent Number: 6,251,394

Title: Method and a system for enhanced in vivo clearance of diagnostic and/or therapeutic agents by extracorporeal depletion, and the use of said agents for said purpose

Abstract: A method and a system is described for reducing non-target levels of specific molecules intended for diagnostic and/or therapeutic applications to vertebrate hosts, wherein said molecules are administered to a vertebrate host and kept therein for a certain time in order to be concentrate to the target by being attached thereto. The molecules which are not attached to the target are removed from the blood circulation system or at least reduced to a lower concentration by passing the blood through an extra-corporeal device.

Inventors: Nilsson; Rune (Lund, SE), Lindgren; Lars (Lund, SE), Norrgren; Kristina (.ANG.karp, SE), Sandberg; Bengt (Lund, SE), Sjogren; Hans Olof (Lund, SE), Strand; Sven-Erik (Lund, SE)

Assignee: Mitra Medical Technology AB

International Classification: A61K 47/48 (20060101); A61K 51/10 (20060101); A61K 51/02 (20060101); A61M 1/36 (20060101); A61K 039/00 ()

Expiration Date: 06/26/2018