Patent Number: 6,251,404

Title: Method of producing a vaccine which raises an immunological response against a virus causing a porcine respiratory and reproductive disease

Abstract: The present invention provides a vaccine which protects pigs from a virus and/or an infectious agent causing a porcine respiratory and reproductive disease, a method of protecting a pig from a disease caused by a virus and/or an infectious agent which causes a respiratory and reproductive disease, a method of producing a vaccine against a virus and/or an infectious agent causing a porcine reproductive and respiratory disease, and a biologically pure sample of a virus and/or infectious agent associated with a porcine respiratory and reproductive disease, particularly the Iowa strain of porcine reproductive and respiratory syndrome virus (PRRSV), and an isolated polynucleotide which is at least 90% homologous with a polynucleotide obtained from the genome of a virus and/or infectious agent which causes a porcine respiratory and reproductive disease.

Inventors: Paul; Prem S. (Ames, IA), Halbur; Patrick G. (Ames, IA), Meng; Xiang-Jin (Ames, IA), Lyoo; Young S. (Ames, IA), Lum; Melissa Anne (Mendota Heighta, MN)

Assignee: Iowa State University Research Foundation

International Classification: A61K 39/12 (20060101); C07K 14/005 (20060101); C07K 14/08 (20060101); C12N 7/00 (20060101); G01N 33/569 (20060101); A61K 39/00 (20060101); A61K 039/12 (); A61K 039/193 (); G01N 033/53 (); C12N 007/00 ()

Expiration Date: 06/26/2018