Patent Number: 6,251,438

Title: Method of preparing active substances from nacre, products obtained which can be used in particular as medicaments

Abstract: This invention relates to a method for preparation of biologically active substances and has the following characteristic features: (a) nacre is reduced to a powder whose grain size is less than approximately 200 .mu.m; (b) it is placed in close contact with an aqueous solvent, (c) at the end of the contact period, the insoluble fraction is separated out to give the aqueous fraction; (d) the solvent of the aqueous fraction is concentrated to separate out the soluble or water-transportable fraction of the nacre, which is made up of biologically active substances with essentially no mineral components. The invention likewise relates to the products obtained by this method, their use for medicinal purposes and the compositions containing them.

Inventors: Lopez; Evelyne (Paris, FR), Giraud; Michel (Melgven, FR), Berland; Sophie (Taverny, FR), Milet; Christian (Saint-Pierre-les-Nemours, FR), Gutierrez; Gilles (Lyons, FR)

Assignee: Centre National de la Recherche Scientifique (CNRS)

International Classification: A61K 35/56 (20060101); A61K 38/17 (20060101); C07K 14/435 (20060101); A61K 38/00 (20060101); A61K 035/56 ()

Expiration Date: 06/26/2018