Patent Number: 6,251,439

Title: Composition and method for reducing the risk of carcinogenesis

Abstract: A method for reducing a risk of carcinogenesis in a subject comprising administering a dose of calcium to the subject that is effective to reduce carcinogenesis. Particularly provided is a method for reducing the risk of recurrence of colorectal adenomas, comprising administering a dose of calcium carbonate effective to reduce the risk of colorectal adenomas. In an example, 1200 mg of elemental calcium (supplied in 3000 mg of calcium carbonate) administered twice daily resulted in decreased risk of recurrent colorectal adenomas in patients with a history of colorectal adenomas.

Inventors: Baron; John A. (Norwich, VT)

Assignee: Trustee of the Dartmouth College

International Classification: A61K 33/42 (20060101); A61K 33/06 (20060101); A61K 33/08 (20060101); A61K 31/185 (20060101); A61K 31/19 (20060101); A01N 059/08 ()

Expiration Date: 06/26/2018