Patent Number: 6,251,603

Title: Method for determining status of a cancerous condition by determining antibodies to NY-ESO-1 in a patient sample

Abstract: The invention relates to methods for determining tumor status by determining antibodies specific to NY-ESO-1 in patient samples. One can determine whether a cancerous condition is progressing, regressing, or remaining stable by determining antibodies against NY-ESO-1 in a patient sample, and comparing the value obtained to a prior value. When the tumor in question expresses NY-ESO-1, a change in this value is indicative of a change in status of the cancerous condition.

Inventors: Jager; Elke (Frankfurt am Main, DE), Stockert; Elisabeth (New York, NY), Old; Lloyd J. (New York, NY), Knuth; Alexander (Frankfurt am Main, DE)

Assignee: Ludwig Institute for Cancer Research

International Classification: C07K 14/435 (20060101); C07K 16/18 (20060101); C07K 14/47 (20060101); A61K 38/00 (20060101); A61K 39/00 (20060101); C12Q 001/68 (); C12P 019/34 (); G01N 033/566 (); C07H 021/04 (); C07K 016/00 ()

Expiration Date: 06/26/2018