Patent Number: 6,251,628

Title: Isolated nucleic acid molecules encoding Smad7

Abstract: The invention describes nucleic acids encoding the Smad7 protein, including fragments and biologically functional variants thereof. Also included are polypeptides and fragments thereof encoded by such nucleic acids, and antibodies relating thereto. Methods and products for using such nucleic acids and polypeptides also are provided.

Inventors: Nakao; Atsuhito (Chiba, JP), Heldin; Carl-Henrik (Uppsala, SE), Dijke; Peter Ten (Uppsala, SE)

Assignee: Ludwig Institute for Cancer Research

International Classification: C07K 14/435 (20060101); C07K 14/47 (20060101); A61K 38/00 (20060101); A61K 48/00 (20060101); C12P 021/02 (); C07H 021/04 (); C12N 001/00 (); C12N 005/10 (); C12N 015/63 ()

Expiration Date: 06/26/2018