Patent Number: 6,251,631

Title: nadE from Streptococcus pneumoniae

Abstract: The invention provides nadE polypeptides and polynucleotides encoding nadE polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing nadE polypeptides to screen for antibacterial compounds.

Inventors: Biswas; Sanjoy (Paoli, PA), Burnham; Martin Karl Russel (Barto, PA), Chalker; Alison Francis (Trappe, PA), Ingraham; Karen Anne (Auburn, PA), Traini; Christopher Michael (Media, PA), Warren; Patrick Vernon (Philadelphia, PA), Zalacain; Magdalena (West Chester, PA)

Assignee: SmithKline Beecham Corporation

International Classification: C07K 14/195 (20060101); C07K 14/315 (20060101); C12N 9/00 (20060101); A61K 38/00 (20060101); A61K 39/00 (20060101); C07K 014/315 (); C12N 005/10 (); C12N 015/11 (); C12N 015/64 ()

Expiration Date: 06/26/2018