Patent Number: 6,251,632

Title: Canine factor VIII gene, protein and methods of use

Abstract: The present invention provides isolated nucleic acid molecules encoding canine factor VIII and allelic variants, mutants, fragments or derivatives thereof. The invention also provides canine factor VIII polypeptides encoded by such isolated nucleic acid molecules, antibodies binding to such polypeptides, genetic constructs comprising such nucleic acid molecules, prokaryotic or eukaryotic host cells comprising such genetic constructs, and methods and compositions for use in diagnosing and treating canine disorders characterized by factor VIII deficiency

Inventors: Lillicrap; David (Joyceville, CA), Cameron; Cherie (Kingston, CA), Notley; Colleen (Kingston, CA), Hoyle Horrocks; L. Suzanne (Whitby, CA), Hough; Christine (Gananoque, CA)

Assignee: Queen's University at Kingston

International Classification: C07K 14/435 (20060101); C07K 14/755 (20060101); C12P 021/00 (); C07H 021/04 (); C12N 015/63 (); C12N 001/21 ()

Expiration Date: 06/26/2018