Patent Number: 6,251,636

Title: Recombinant oleandolide polyketide synthase

Abstract: Recombinant DNA compounds that encode all or a portion of the oleandolide polyketide synthase are used to express recombinant polyketide synthase genes in host cells for the production of oleandolide, oleandolide derivatives, and polyketides that are useful as antibiotics and motilides.

Inventors: Betlach; Mary C. (San Francisco, CA), Shah; Sanjay Krishnakant (Concord, CA), McDaniel; Robert (Palo Alto, CA), Tang; Li (Foster City, CA)

Assignee: Kosan Biosciences, Inc.

International Classification: C12P 19/00 (20060101); C12P 19/62 (20060101); C12N 15/52 (20060101); C12P 019/62 ()

Expiration Date: 06/26/2018